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. 2015 Feb 12;2:3. doi: 10.1186/s40662-015-0013-7

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© Liu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Estimation of changes of RNFLT of clock hour 1, 2 and 10 average over time. The left column is before registration, right column is after registration. The dashed lines are the fits of individual primates. The individual fits display very similar trends as compared to the linear mixed effects model fits. The clock hour 1 and 2 averages decreased significantly before registration (p = 0.0058 for clock hour 1 and p = 0.0054 for clock hour 2), but stayed constant after registration. The clock hour 10 average RNFLT increased significantly before registration (p = 0.0298), but was constant after registration.