Table 1.
Subject number | Gender | Age | Follow-up (months) | H/M ratio | Possibly interfering medication | Cardiovascular comorbidity, LVEF (if available) | Follow-up diagnosis | Core features of DLB | Suggestive features of DLB |
---|---|---|---|---|---|---|---|---|---|
1 | M | 73 | 7 | 1.71 | – | Hyperlipidemia, AHT, IHD, LVEF 59% | No dementia | ||
2 | F | 81 | 7 | 1.41 | – | AHT, LVEF 60% | DLB | F/H/P | |
3 | M | 79 | 10 | 1.10 | – | DLB | F/H/P | ||
4 | M | 73 | 6 | 1.30 | – | AHT, IHD, heart failure | DLB | H/P | Positive DAT scan |
5 | M | 78 | 1 | 1.76 | – | – | Definite AD | H/P | |
6 | M | 87 | 11 | 1.62 | – | – | DLB | F/H/P | |
7 | M | 77 | 8 | 1.47 | Trazodone | LVEF 63% | AD with CVD | H | |
8 | M | 78 | 19 | 1.05 | – | DLB | F | ||
9 | M | 76 | 21 | 1.10 | – | IHD, heart failure | DLB | H/P | |
10 | F | 83 | 17 | 1.24 | – | – | DLB | P | Severe neuroleptic sensitivity |
11 | F | 75 | 17 | 1.38 | – | AHT, AF, myocardial hypertrophy, LVEF 65% | DLB | F | |
12 | M | 71 | 15 | 1.34 | Trazodone | AHT, LVEF 70% | DLB | F/H/P | |
13 | M | 72 | 8 | 1.23 | – | AHT, AF | DLB | P | |
14 | M | 72 | 44 | 2.20 | – | – | AD | F/H/P | Severe neuroleptic sensitivity |
15 | F | 81 | 6 | 0.97 | – | – | DLB | P | Positive DAT scan |
16 | F | 79 | 18 | 1.44 | – | – | AD + PD | P | |
17 | M | 84 | 31 | 1.11 | Trazodone | Hyperlipidemia, AHT | DLB | F | Positive DAT scan and REM sleep behavior disorder |
18 | M | 75 | 6 | 1.61 | Trazodone | – | DLB | H/P | Severe neuroleptic sensitivity |
19 | M | 74 | 13 | 0.99 | Trazodone | Hyperlipidemia, IHD, AF | DLB | F/H/P | |
20 | M | 75 | 57 | 1.07 | – | PDD | F/H/P | REM sleep behavior disorder |
Abbreviations: AF = atrial fibrillation; AHT = arterial hypertension; DLB = dementia with Lewy bodies; H = visual hallucinations; IHD = ischemic heart disease; F = fluctuating cognition; LVEF = left ventricular ejection fraction; P = Parkinsonism; DAT = dopamine transporter imaging; CVD = cerebrovascular disease; PD = Parkinson’s disease.