Figure 7.

Chemoinformatic analysis of chemical similarity relations (Tanimoto indices) between different structural classes of nicotinic acetylcholine receptor agonists and their derivative-revealed structure-based clusters. Line thickness and grey level encode Tanimoto similarity values. Solid lines are used for similarities greater than 50%. In order to avoid a disconnected graph, the fourth highest similarity relationship for each of the small, triangular-shaped clusters is given as a dashed line.