Table 4.
Association of Demographic and Health Characteristics at Study Entry With Mortality Risk in P1074 Subjects
| Characteristica | Unadjusted Models |
Adjusted Modelb (n = 1197) |
|||
|---|---|---|---|---|---|
| Subjects, No. | HR (95% CI) | P Value | HR (95% CI) | P Value | |
| Age at first chart review | 1201 | 1.18 (1.10–1.28) | <.001 | 1.09 (.98–1.22) | .10 |
| CD4 cell count at first chart review (for each 50-cell/mm3 increase) | 1197 | 0.71 (.64–.79) | <.001 | 0.78 (.68–.88) | <.001 |
| HIV RNA at first chart review (for each log10 copies/mL increase) | 1201 | 3.02 (2.18–4.17) | <.001 | 1.45 (.99–2.13) | .054 |
| Sex (female vs male) | 1201 | 2.02 (.91–4.46) | .08 | … | … |
| BMI z score at first chart review | 1084 | 0.86 (.61–1.22) | .40 | … | … |
| Black race | 1201 | 1.10 (.51–2.38) | .81 | … | … |
| Hispanic ethnicity | 1201 | 0.85 (.36–2.00) | .71 | … | … |
| Receiving cART at first chart review | 1179 | 0.82 (.28–2.37) | .71 | … | … |
| Perinatal HIV acquisition (yes vs no) | 1196 | 1.15 (.35–3.80) | .82 | … | … |
Abbreviations: BMI, body mass index; cART, combination antiretroviral therapy; CI, confidence interval; HIV, human immunodeficiency virus; HR, hazard ratio.
a Characteristics were the latest available measurements prior to or on the date of the first chart abstraction.
b Adjusted model includes only those covariates with estimates provided (age, CD4 cell count, HIV RNA).