TABLE 1.
Demographic Characteristics of Patients Without Prevalent Diabetes Who Did and Did Not Initiate Statin Therapy, the HOPS, 2002–2011 (N = 4692)
| Characteristic | Not Prescribed Statins N= 4102 (87.4%) | Prescribed Statins N= 590 (12.6%) | P |
|---|---|---|---|
| Age at index date, n (%), yrs* | <0.001 | ||
| <35 | 1218 (29.7) | 60 (10.2) | |
| 35–49 | 2244 (54.7) | 370 (62.7) | |
| ≥50 | 640 (15.6) | 160 (27.1) | |
| Age at index date, median (IQR) | 40 (34–46) | 44 (40–50) | <0.001 |
| Sex, n (%) | 0.077 | ||
| Female | 918 (22.4) | 113 (19.2) | |
| Male | 3184 (77.6) | 477 (80.8) | |
| Race/ethnicity, n (%) | <0.001 | ||
| Non-Hispanic/Latino white | 2006 (48.9) | 347 (58.8) | |
| Non-Hispanic/Latino black | 1451 (35.4) | 150 (25.4) | |
| Hispanic/Latino | 483 (11.8) | 68 (11.5) | |
| Other/unknown | 162 (3.9) | 25 (4.2) | |
| Antiretroviral history at index date, n (%) | <0.001 | ||
| Experienced | 2688 (65.5) | 442 (74.9) | |
| Naive | 1096 (26.7) | 109 (18.5) | |
| Unknown | 318 (7.8) | 39 (6.6) | |
| HIV transmission risk, n (%) | 0.056 | ||
| Heterosexual | 1099 (26.8) | 154 (26.1) | |
| Injection drug use | 388 (9.5) | 45 (7.6) | |
| Men who have sex with men | 2308 (56.3) | 360 (61) | |
| Other/unknown | 307 (7.5) | 31 (5.3) | |
| Insurance, n (%) | 0.080 | ||
| Private | 2195 (53.5) | 338 (57.3) | |
| Public | 1537 (37.5) | 213 (36.1) | |
| Other/unknown | 370 (9.0) | 39 (6.6) | |
| AIDS at index date, n (%) | 0.016 | ||
| No | 2322 (56.6) | 303 (51.4) | |
| Yes | 1780 (43.4) | 287 (48.6) | |
| Prevalent hepatitis C at index date, n (%) | <0.001 | ||
| No | 3483 (84.9) | 536 (90.8) | |
| Yes | 619 (15.1) | 54 (9.2) | |
| BMI at index date, n (%), kg/m2 | 0.003 | ||
| <25 | 2022 (49.3) | 255 (43.2) | |
| 25–29 | 1208 (29.4) | 193 (32.7) | |
| ≥30 | 567 (13.8) | 107 (18.1) | |
| Unknown | 305 (7.4) | 35 (5.9) | |
| CD4 cell count (cells/mm3) at index date, n (%)† | 0.071 | ||
| <50 | 280 (6.8) | 29 (4.9) | |
| 50–199 | 499 (12.2) | 66 (11.2) | |
| 200–349 | 703 (17.1) | 100 (16.9) | |
| 350–499 | 697 (17.0) | 105 (17.8) | |
| ≥500 | 1240 (30.2) | 215 (36.4) | |
| Unknown | 683 (16.7) | 75 (12.7) | |
| CD4 cell count, median (IQR) | 394 (216–593) | 430 (260–658) | <0.001 |
| Viral load (copies/mL) at index date, n (%)† | <0.001 | ||
| 0–1000 | 1584 (38.6) | 295 (50.0) | |
| 999–99,999 | 1318 (32.1) | 153 (25.9) | |
| ≥100,000 | 498 (12.1) | 47 (8.0) | |
| Unknown | 702 (17.1) | 95 (16.1) | |
| Log10 viral load, median (IQR) | 3.3 (1.7–4.6) | 2.4 (1.4–4.3) | <0.001 |
*
Index date is the date of the first HOPS visit in 2002 or thereafter.
†
Closest laboratory measurement up to 6 months before and 1 week after index date.
IQR, interquartile range.