Table 2. Volumetric analysis is presented as mean and s.d. of volume measurement for striatal regions of interest.
| UHR | Control | Total | P⩽ | |
|---|---|---|---|---|
| Ipsilateral putamen | ||||
| Mean (s.d.) | 0.35 (0.04) | 0.37 (0.03) | 0.36 (0.04) | 0.001 |
| 95% CI | 0.34, 0.36 | 0.36, 0.39 | 0.35, 0.37 | |
|
Contralateral putamen
| ||||
| Mean (s.d.) | 0.36 (0.04) | 0.39 (0.04) | 0.38 (0.04) | 0.001 |
| 95% CI | 0.35, 0.37 | 0.38, 0.40 | 0.37, 0.39 | |
|
Left caudate
| ||||
| Mean (s.d.) | 0.24 (0.02) | 0.25 (0.02) | 0.24 (0.02) | NS |
| 95% CI | 0.24, 0.25 | 0.24, 0.25 | 0.24, 0.25 | |
|
Right caudate
| ||||
| Mean (s.d.) | 0.24 (0.03) | 0.25 (0.02) | 0.24 (0.02) | NS |
| 95% CI | 0.23, 0.25 | 0.24, 0.25 | 0.24, 0.25 | |
Abbreviations: NS, not significant; UHR, ultrahigh risk.
All volumes are expressed as the percent of total intracranial volume (TICV). UHR individuals showed significant volume reduction in the ipsilateral and contralateral putamen. 95% Confidence interval (CI) expressed as lower bound, upper bound.