Table 3.

Summary ORs and 95%CI of TLR4 +896A/G and +1196C/T polymorphisms and asthma risk.

Subgroup	Genetic model	Genotype/Allele	Type of model	Heterogeneity		Test of association
				I2	P	OR	95%CI	P
+896A/G
Overall	Dominant model	GG+AG vs. AA	Fixed	0.0%	0.99	1.05	0.89–1.24	0.56
	Codominant model	AG vs. AA	Fixed	0.0%	0.97	1.04	0.88–1.23	0.64
	Allele model	G vs. A	Fixed	0.0%	0.97	1.05	0.90–1.23	0.51
Caucasians	Dominant model	GG+AG vs. AA	Fixed	0.0%	1.00	1.14	0.92–1.41	0.22
	Codominant model	AG vs. AA	Fixed	0.0%	0.96	1.12	0.90–1.39	0.32
	Allele model	G vs. A	Fixed	0.0%	0.99	1.16	0.95–1.42	0.15
Asians	Dominant model	GG+AG vs. AA	Fixed	0.0%	0.62	0.91	0.69–1.19	0.48
	Codominant model	AG vs. AA	Fixed	0.0%	0.74	0.92	0.69–1.22	0.56
	Allele model	G vs. A	Fixed	0.0%	0.52	0.91	0.71–1.16	0.43
+1196C/T
Overall	Dominant model	TT+CT vs. CC	Fixed	0.0%	0.83	0.76	0.59–0.96	0.03
	Codominant model	CT vs. CC	Fixed	0.0%	0.75	0.74	0.58–0.95	0.02
	Allele model	T vs. C	Fixed	0.0%	0.87	0.79	0.63–0.99	0.04
Caucasians	Dominant model	TT+CT vs. CC	Fixed	0.0%	0.52	0.84	0.57–1.24	0.39
	Codominant model	CT vs. CC	Fixed	0.0%	0.40	0.82	0.55–1.22	0.33
	Allele model	T vs. C	Fixed	0.0%	0.65	0.87	0.60–1.26	0.46
Asians	Dominant model	TT+CT vs. CC	Fixed	0.0%	0.84	0.70	0.51–0.96	0.03
	Codominant model	CT vs. CC	Fixed	0.0%	0.89	0.69	0.50–0.96	0.03
	Allele model	T vs. C	Fixed	0.0%	0.67	0.73	0.54–0.98	0.04