Table 2.

Demographic and neuropathological features in controls and in Alzheimer patients without (AD) and with cerebral amyloid angiopathy (AD-CAA)

Items	Control (n= 12)	AD (n= 12)	AD-CAA (n= 8)
Age: years (interquartile range)	64 (60-78)	68 (63-76)	70 (63-88)
Gender (% males)	67	67	50
Vascular risk factors (%)
Arterial hypertension	17	42	38
Diabetes	17	17	25
Hypercholesterolemia	17	17	25
Smoking	0	8	13
Antithrombotic drug use	25	33	50
Neuropathological lesions: mean values (SD)
White matter changes	0.3 (0.8)	0.8 (0.8)	1.3 (1.3)
Lacunar infarcts	0.0 (0.0)	0.0 (0.0)	0.3 (0.7)
Territorial infarcts	0.0 (0.0)	0.1 (0.3)	0.0 (0.0)
Lobar haematomas	0.0 (0.0)	0.0 (0.0)	0.0 (0.0)
Cortical microinfarcts	0.1 (0.3)	0.8 (1.1)	1.4 (1.1)*
Cortical microbleeds	0.1 (0.3)	0.4 (0.7)	1.1 (0.6)*

^*= p value ≤ 0.01 between the brains with Alzheimer disease associated with cerebral amyloid angiopathy, and the controls.