Table 3.
Mean numbers of cortical microbleeds with standard deviations between bracquets in the different gyri of control and Alzheimer brains without (AD) and with cerebral amyloid angiopathy (AD-CAA)
| Gyrus | C (n= 12) | AD (n= 12) | AD-CAA (n= 8) | P value AD/AD-CAA |
|---|---|---|---|---|
| Frontalis inferior | 0.8 (0.9) | 2.3 (2.7) | 4.8 (2.9)** | 0.03 |
| Frontalis medius | 1.2 (1.4) | 1.9 (1.4) | 4.3 (2.5)* | 0.03 |
| Frontalis superior | 1.2 (1.4) | 3.1 (1.8)* | 6.7 (3.4)** | 0.02 |
| Precentralis | 1.1 (1.5) | 2.1 (1.3) | 2.8 (0.8)* | 0.27 |
| Rectus | 0.4 (0.7) | 1.5 (1.2)* | 4.4 (3.8)** | 0.07 |
| Orbitalis | 0.8 (1.1) | 2.1 (2.0) | 4.3 (1.6)** | 0.02 |
| Temporalis inferior | 0.4 (1.0) | 2.6 (3.0)* | 3.4 (2.6)** | 0.30 |
| Temporalis medius | 0.5 (0.8) | 1.9 (1.9) | 3.7 (2.9)** | 0.16 |
| Temporalis superior | 0.6 (1.1) | 1.5 (1.2) | 3.9 (3.2)** | 0.06 |
| Hippocampus | 0.4 (0.8) | 0.8 (0.8) | 1.1 (1.6) | 1.0 |
| Dentatus | 0.7 (1.2) | 1.9 (2.1) | 2.4 (1.7)* | 0.38 |
| Parahippocampalis | 0.5 (1.1) | 1.0 (1.6) | 2.0 (1.2)* | 0.05 |
| Postcentralis | 0.7 (0.9) | 2.3 (2.6) | 2.9 (1.6)** | 0.18 |
| Insula | 0.0 (0.0) | 1.8 (2.7)* | 2.4 (1.8)** | 0.18 |
| Parietalis inferior | 0.3 (0.4) | 0.7 (0.6) | 2.9 (2.2)** | 0.001** |
| Parietalis medius | 1.2 (1.4) | 1.7 (1.0) | 2.9 (2.6) | 0.34 |
| Parietalis superior | 0.6 (0.5) | 1.7 (1.6) | 2.7 (2.3)* | 0.31 |
| Cinguli | 0.4 (0.6) | 1.5 (1.7)* | 3.0(2.0)** | 0.02 |
| Lingualis | 0.3(0.9) | 1.4(2.7) | 2.9(2.2)** | 0.03 |
| Precuneus | 0.6 (1.0) | 0.9 (1.6) | 3.3 (2.8)* | 0.01* |
| Cuneus | 0.5 (0.9) | 0.8 (1.5) | 3.2 (2.6)* | 0.01* |
| Occipitotemporalis | 0.6 (1.0) | 2.4 (2.2) | 4.6 (3.0)** | 0.18 |
*
= p value ≤ 0.01;
**
= p value ≤ 0.001 comparing AD, AD-CAA and control brains.