Table 1.

Blood profile of WT and KO nondiabetic or STZ-induced diabetic mice 24 weeks after the first set of STZ injections

Blood Profile	TxNIP- WT		TxNIP- KO
	Nondiabetic	Diabetic	Nondiabetic	Diabetic
Blood glucose (mmol/L)	6.47±0.38	21.76±1.40a	5.99±0.32	20.33±1.73b
Plasma glucose (mmol/L)	9.68±0.64	21.68±1.49a	8.5±1.09	20.83±1.60b
HbA1c (%)	4.53±0.06	6.93±0.40c	4.2±0.15	6.62±0.58d
Hb (g/L)	143±11.67	145±3.49	133.5±11.72	133±7.43
RBC (1012 cells/L)	9.24±0.69	9.21±0.33	8.51±0.76	8.32±0.50
WBC (109 cells/L)	5.32±0.81	10.28±0.57e	6.97±1.07	9.57±2.96
Serum ketone bodies: β-hydroxybutyrate (nmol)	0.12±0.02	0.2±0.036	0.28±0.06	0.30±0.01
Serum insulin (ng/ml)	0.25±0.04	0.16±0.01f	0.21±0.03	0.12±0.01f
Serum lactate (nmol/L)	6.67±0.86	8.85±0.82	9.25±1.44	17.4±1.53g

Values are expressed as mean±SEM. HbA_1c, hemoglobin A_1c; Hb, hemoglobin; RBC, red blood cell; WBC, white blood cell.

^aP<0.0001 versus WT nondiabetic mice.

^bP<0.0001 versus KO nondiabetic mice.

^cP<0.001 versus WT nondiabetic mice.

^dP<0.01 versus KO nondiabetic mice.

^eP<0.01 versus WT nondiabetic mice.

^fP<0.05 versus nondiabetic WT mice.

^gP<0.05 diabetic KO mice versus all other groups.