Skip to main content
. 2015 Apr 8;26(12):2953–2962. doi: 10.1681/ASN.2014080816

Figure 2.

Figure 2.

AT1A receptors in VSMCs promote the hypertensive response to low-dose Ang II–dependent hypertension. (A) Daily radiotelemetry tracings from control mice (closed squares) and SMKO mice (open triangles) infused with chronic low-dose Ang II (400 ng/kg per min) over 1 week. (B) Control mice developed robust hypertension with an increase in MAP of 25±5 mmHg from baseline during the first week of Ang II administration. The increase in MAP was significantly attenuated in SMKO mice (8±2 mmHg; *P<0.01, open triangles, unpaired t test).