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Frequency of Tregs and intracellular cytokines by lymphocytes isolated from inguinal LN and thymus at baseline. (A) The percentage of Tregs is significantly higher in the LN in CD4-Keap1-KO at baseline than in Keap1F/F mice. (B and C) Baseline intracellular TNF-α, IFN-γ, and IL-17 is lower in CD4, CD8, and DNT cells isolated from CD4-Keap1-KO LN (B) and thymus (C) than in Keap1F/F counterparts. Data represent the mean±SD. *P≤0.05; **P≤0.01.
