Table 1.
Association of conventional diagnosis with v-lesion grade and failures in 49 biopsies with v-lesions, identified in 703 indication biopsies from 564 kidneys
| Conventional Diagnosis | v1 (n=36) | v2 (n=11) | v3 (n=2) | Total (n=49) | No. Failed (No. in Each v-Lesion Grade) (n=10) |
|---|---|---|---|---|---|
| Pure TCMR | 24 | 5 | 1 | 30 (61%) | 5 (all v1) |
| Mixed | 10 | 6 | 1 | 17 (35%) | 5 (v1: n=4; v2: n=1) |
| No rejection | 2a | 0 | 0 | 2 (4%) | 0 |
| No. failed in each v-lesion grade | 9 | 1 | 0 | 10 |
Thirty biopsies were deleted from the analyses because no v-lesion was recorded. One biopsy previously called pure ABMR was recently reviewed and reclassified as TCMR, making these numbers slightly different from previous analyses.
a
Histologic lesions indicating TCMR are often not reported as rejection in biopsies with polyoma virus nephropathy because of uncertainty about whether the lesions reflect rejection versus virus effects (see text).