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. 2015 Nov 23;10(11):e0143171. doi: 10.1371/journal.pone.0143171

Fig 6. Rotundifolone and the cooling compound menthol enhanced the vasorelaxation effect induced by cold temperatures in rat mesenteric arteries by increasing calcium influx.

Fig 6

Bar graph summary showing that the response induced by 3x10-3 M rotundifolone (A) or 10–3 M menthol (B) (n = 6) in the vasodilatation induced by cold temperatures in rat superior mesenteric arteries rings without vascular endothelium was attenuated in the presence of EGTA. Data are the mean ± SEM. The data were examined using one-way ANOVA followed by the Bonferroni post-test. *p < 0.05; **p < 0.01 and ***p < 0.001 rotundifolone or menthol vs control; ###p < 0.001 vs rotundifolone or menthol.