Table 5. Selectivity: Drugs concomitantly administered with ifosfamide.
| Drug administered | Drug concentration (mg/mL) | Molecular ion m/z ratio | Fragment ion m/z ratio | 30% HTC Mean ± SD %CV | 45% HTC Mean ± SD %CV |
|---|---|---|---|---|---|
| Etoposide | 0.24 | 589.0 | 229.0 | 2502.3±177.9 7.1 | 2524.5± 87.6 3.4 |
| Carboplatin | 10.00 | 372.1 | 355.0 | 2513.1± 200.0 7.9 | 2460.8±45.1 1.8 |
| Vincristin | 0.10 | 825.6 | 138.0 | 2364.87±152.2 6.4 | 2501.8±40.1 1.6 |
| Methotrexate | 11.50 | 455.2 | 308.2 | 2394.9± 88.5 3.7 | 2551.8±150.0 5.8 |
| Ondansetron | 0.25 | 294.2 | 169.7 | 2594.1± 175.9 6.7 | 2627.7±126.0 4.8 |
The concentration of each drug was determined according to which it is administered in clinical practice. SD: Standard Deviation calculated from three independent repeats (n = 3).