Table 2. Correlation of lgr5 methylation with clinicopathological features of colorectal cancer patients.

Clinicopathological feature	n	Lgr5 methylation (%)	χ2	p
Total	169	67 (40%)
Gender
Female	68	30 (44%)	0.951	0.341
Male	101	37 (37%)
Age (years)
≥ 60	75	27 (36%)	0.749	0.431
< 60	94	40 (43%)
Tumor position
Rectum	109	45 (41%)	4.899	0.179
Left colon	19	4 (21%)
Transverse colon	19	6 (32%)
Right colon	23	12 (52%)
Dukes stage
A	51	21 (33%)	5.618	0.132
B	56	27 (36%)
C	31	12 (39%)
D	31	7 (25%)
Tumor grade
High	85	47 (31%)	18.84	<0.001
Moderate	52	15 (38%)
Low	32	5 (16%)
Nodal status
Positive	31	12 (17.9%)	0.014	0.04
Negative	138	55(39%)
Distal metastasis
Positive	31	7 (25%)	4.620	0.024
Negative	138	60(51.1%)

Note: p value was calculated using Pearson’s χ² test.