Table 1. Demographic characteristics of the study populations.
| IRASFS | Replication Cohorts | |||||||
|---|---|---|---|---|---|---|---|---|
| GWAS | Exome Chip | IRAS | TRIPOD | BetaGene | HTN-IR | MACAD | NIDDM-Athero | |
| n | 1034 | 1263 c | 184 | 125 | 1218 | 666 | 749 | 179 |
| Male (%) | 41.1 | 41.1 | 41.1 | 0 | 28.4 | 40.6 | 43.3 | 41.8 |
| Age (years) b | 40.6±13.7 | 42.8±14.6 | 54.0±8.2 | 34.8±6.3 | 34.5±8.2 | 37.4±14.2 | 34.5±8.8 | 31.8±9.69 |
| Body Mass Index (BMI; kg/m 2) b | 28.3±5.8 | 28.9±6.1 | 28.2±5.1 | 30.6±5.4 | 29.5±6.1 | 28.8±5.5 | 28.9±5.1 | 28.6±6.3 |
| Waist circumference (WAIST; cm) b | 88.2±13.6 | 89.4±15.5 | 90.1±12.2 | 91.4±12.6 | 94.2±14.0 | 90.7±14.5 | 92.7±12.5 | 91.3±14.8 |
| Waist Hip Ratio (WHR) b | 0.85±0.083 | 0.86±0.085 | 0.87±0.088 | 0.86±0.061 | 0.89±0.073 | 0.88±0.084 | 0.89±0.076 | 0.84±0.087 |
| Subcutaneous Adipose Tissue (SAT; cm 2) b | 329.8±151.7 | 339.1±154.7 | NA | NA | NA | NA | NA | NA |
| Visceral Adipose Tissue (VAT; cm 2) b | 106.6±57.0 | 114.0±61.3 | NA | NA | NA | NA | NA | NA |
| Percent Body Fat (PBF) b | 33.5±8.7 | 34.0±8.7 | NA | NA | 34.4±8.4 | 32.6±9.1 a | 32.2±8.3 | NA |
aHTN-IR has only 139 individuals with PBF measurements
bValues are expressed as the mean ± standard deviation
cIncludes 161 diabetics
Abbreviations: IRASFS, Insulin Resistance Atherosclerosis Family Study; IRAS, Insulin Resistance Atherosclerosis Study; TRIPOD, Troglitazone in Prevention of Diabetes Study; BetaGene, Family-based study of obesity, insulin resistance, and beta-cell dysfunction; HTN-IR, Hypertension-Insulin Resistance Family Study; MACAD, Mexican-American Coronary Artery Disease Study; NIDDM-Athero, NIDDM-Atherosclerosis Study.