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. 2015 Nov 24;10(11):e0134649. doi: 10.1371/journal.pone.0134649

Table 2. Significant signals of association from genome-wide and exome chip association analyses in IRASFS.

SNP Chr: Position (hg19) Gene Alleles f N MAF e Beta+/-SE P-Value
Body Mass Index (BMI)
rs34218846 b 2:209108317 IDH1 T/C 1253 0.070 -0.10±0.020 4.81E-08 c
Waist Circumference (WAIST)
rs34218846 b 2:209108317 IDH1 T/C 1257 0.068 -0.080±0.010 1.62E-08 c
Waist-Hip Ratio (WHR)
rs1471880 a 4:113546107 ZGRF1 C/A 1034 0.48 -0.027±0.0047 1.00E-08 c
rs13144672 a 4:113472958 ZGRF1 C/T 1034 0.47 0.027±0.0048 3.15E-08 d
rs12054518 a 4:113549989 ZGRF1 A/G 1034 0.48 0.027±0.0048 3.23E-08 d
rs7696816 a 4:113539969 ZGRF1 C/T 1034 0.48 0.027±0.0048 4.35E-08 d

aSNP identified from GWAS

bSNP identified from exome chip

cDominant Model

dRecessive Model

eMinor allele frequency based on the entire population

fMinor/Major allele on the positive strand