. 2015 Nov 24;10(11):e0134649. doi: 10.1371/journal.pone.0134649

Table 3. Fixed-effect meta-analysis results (P<2.0x10^-3) for significant signals of association (5.00x10^-6) from IRASFS.

SNP	Chr:Position (hg19)	Alleles ^b	Effect	SE	Direction ^f	Gene Name	P-value
*Waist Circumference (WAIST)* ^a
rs1471880	4:113546107	A/C	0.0221	0.005	+++-++-	ZGRF1	8.38E-06 ^d
rs6435435	2:209112551	A/G	0.0307	0.0077	+-++-++	IDH1	6.74E-05 ^d
rs13144672	4:113472958	A/G	-0.0131	0.0033	---+--+	ZGRF1	6.90E-05 ^c
rs7696816	4:113539969	A/G	-0.0126	0.0033	---+--+	ZGRF1	1.01E-04 ^c
rs12054518	4:113549989	A/G	0.0125	0.0033	+++-++-	ZGRF1	1.24E-04 ^c
rs1869479	11:44343856	A/C	0.0176	0.0047	+-+-++-	HSD17B12/CD82	2.01E-04 ^d
rs6734788	2:209093069	A/G	-0.0194	0.0058	-+-++++	CCNYL1/IDH1	7.98E-04 ^c
rs7937515	11:71841325	A/G	0.0141	0.0046	+-+-++-	FAM86C1/FOLR3	2.00E-03 ^c
*Waist-Hip Ratio (WHR)* ^a
rs7696816	4:113539969	A/G	-0.0116	0.0028	---++--	ZGRF1	4.34E-05 ^e
rs13106629	4:113459416	A/G	0.0116	0.0028	+++--++	C4orf32/ZGRF1	4.39E-05 ^e
rs12054518	4:113549989	A/G	0.0115	0.0028	+++--++	ZGRF1	5.43E-05 ^e
rs2129405	4:113447137	A/G	0.0113	0.0028	+++--++	C4orf32/ZGRF1	6.24E-05 ^e
rs10770244	12:17848331	A/G	-0.0091	0.0023	---++-+	MIR3974/Y_RNA	6.67E-05 ^d
rs13144672	4:113472958	A/G	-0.0111	0.0028	---++--	ZGRF1	7.22E-05 ^e
rs6734788	2:209093069	A/G	-0.0109	0.0028	-+-++-+	CCNYL1/IDH1	9.02E-05 ^c

^aMeta-analysis was computed based on beta and SE

^b Reference/alternate allele

^cAdditive model

^dDominant model

^eRecessive model

^fDirection follows as: IRASFS, IRAS, BetaGene, TRIPOD, HTN-IR, MACAD, NIDDM-Athero

Table 3. Fixed-effect meta-analysis results (P<2.0x10-3) for significant signals of association (5.00x10-6) from IRASFS.