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(A and B) R+G+ stimulates IL-6 production in WT MMs, but not in IL-1-KO MMs. WT and IL-1-KO mice were subjected to 1 h of R+G+ or of R+G-, and then IL-6 mRNA (A) and IL-6 protein (B) in their MMs were measured. Experimental values are given as the mean ± SE (n = 6 for A and n = 6–8 for B). **P < 0.01, NS: not significant.
