Table 2. Relative Bcl-xl, Bak, and Bcl-xl/Bak mRNA in liver of CD and FASD (Mthfr +/+ ) mice at 7 dpi.
mRNA expression | |||
---|---|---|---|
CD | FASD | ||
Bcl-xl | 1.00 ± 0.09 | 1.68 ± 0.25 | p<0.05 |
Bak | 1.00 ± 0.07 | 1.02 ± 0.13 | p>0.05 |
Bcl-xl/Bak | 1.00 ± 0.07 | 1.71 ± 0.163 | p<0.01 |
Expression of Bcl-xl, Bak, and Bcl-xl/Bak in liver of CD mice (n = 9; 3 combined experiments) and FASD mice (n = 9; 3 combined experiments) indicates that FASD murine livers had a lower apoptotic environment (higher Bcl-xl/Bak ratio) compared with that in CD mice.