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. 2015 Nov 24;10(11):e0143738. doi: 10.1371/journal.pone.0143738

Table 2. Relative Bcl-xl, Bak, and Bcl-xl/Bak mRNA in liver of CD and FASD (Mthfr +/+ ) mice at 7 dpi.

mRNA expression
CD FASD
Bcl-xl 1.00 ± 0.09 1.68 ± 0.25 p<0.05
Bak 1.00 ± 0.07 1.02 ± 0.13 p>0.05
Bcl-xl/Bak 1.00 ± 0.07 1.71 ± 0.163 p<0.01

Expression of Bcl-xl, Bak, and Bcl-xl/Bak in liver of CD mice (n = 9; 3 combined experiments) and FASD mice (n = 9; 3 combined experiments) indicates that FASD murine livers had a lower apoptotic environment (higher Bcl-xl/Bak ratio) compared with that in CD mice.