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. 2015 Nov 23;10(11):e0142414. doi: 10.1371/journal.pone.0142414

Table 2. Adjusted treatment effects on changes in hemoglobin 7, 14, and 28 days after an IPTi dose.

Adjusted between-group differences (g/dL) [95%CI]
7 days after an IPTi dose 14 days after an IPTi dose 28 days after an IPTi dose
Treatment Estimate P-value a Overall p-value b Estimate P-value a Overall p-value b Estimate P-value a Overall p-value b
Placebo Ref 0.01 Ref <0.001 Ref 0.07
SP 0.00 [-0.34 to 0.34] 1.0 0.06 [-0.22 to 0.34] 0.7 -0.07 [-0.28 to 0.13] 0.5
MQ 0.10 [-0.26 to 0.45] 0.6 -0.03 [-0.31 to 0.26] 0.8 0.08 [-0.13 to 0.29] 0.5
CD -0.45 [-0.80 to -0.09] 0.01 -0.50 [-0.79 to -0.22] 0.001 -0.19 [-0.40 to 0.01] 0.07

Analyses adjusted for genotype, dose number, sex, site, weight (kg) and elevation (m).

aP-values for adjusted treatment effects compared to chlorproguanil-dapsone (CD).

bP-values for overall adjusted treatment effects. SP = sulfadoxine-pyrimethamine. MQ = mefloquine.