Table 2. Adjusted treatment effects on changes in hemoglobin 7, 14, and 28 days after an IPTi dose.
Adjusted between-group differences (g/dL) [95%CI] | |||||||||
---|---|---|---|---|---|---|---|---|---|
7 days after an IPTi dose | 14 days after an IPTi dose | 28 days after an IPTi dose | |||||||
Treatment | Estimate | P-value a | Overall p-value b | Estimate | P-value a | Overall p-value b | Estimate | P-value a | Overall p-value b |
Placebo | Ref | 0.01 | Ref | <0.001 | Ref | 0.07 | |||
SP | 0.00 [-0.34 to 0.34] | 1.0 | 0.06 [-0.22 to 0.34] | 0.7 | -0.07 [-0.28 to 0.13] | 0.5 | |||
MQ | 0.10 [-0.26 to 0.45] | 0.6 | -0.03 [-0.31 to 0.26] | 0.8 | 0.08 [-0.13 to 0.29] | 0.5 | |||
CD | -0.45 [-0.80 to -0.09] | 0.01 | -0.50 [-0.79 to -0.22] | 0.001 | -0.19 [-0.40 to 0.01] | 0.07 |
Analyses adjusted for genotype, dose number, sex, site, weight (kg) and elevation (m).
aP-values for adjusted treatment effects compared to chlorproguanil-dapsone (CD).
bP-values for overall adjusted treatment effects. SP = sulfadoxine-pyrimethamine. MQ = mefloquine.