Table 2. Clinical history in the total cohort and according to stages of Fabry cardiomyopathy.
Early stage | Intermediate stage | Severe stage | ||||
---|---|---|---|---|---|---|
Baseline (n = 39) | Follow-up (n = 17) | Baseline (n = 23) | Follow-Up (n = 19) | Baseline (n = 12) | Follow-up (n = 10) | |
Bundle branch block | 1 (2.6) | 2 (12) | 1 (4.3) | 2 (10) * | 2 (17) | 4 (40) † |
Cardiac arrhythmia | 3 (7.7) | 3 (18) | 3 (13) | 5 (26) | 2 (17) | 6 (60) † |
Angina pectoris without CAD | 0 | 1 (5.8) | 0 | 2 (10) * | 1 (8.3) | 4 (40) † |
ACVB, Stent or ICD | 1 (2.6) | 1 (5.8) | 0 | 1 (5.3) | 2 (17) | 2 (20) |
Mean observation period of 51 ± 24 months.
* p<0.005 intermediate CM baseline vs. intermediate CM follow-up
† p<0.005 advanced CM baseline vs. advanced CM follow-up
CAD, coronary artery disease
CM, cardiomyopathy
LE, late enhancement
ACVB, aorto-coronary vein bypass
ICD, implanted cardioverter defibrillator.