Table 4. Selected peptides exhibiting IFN-γ response in multiple donors.
| Peptide Id | Peptide sequence | Protein | Pool | Response 1 | DRB1* Binding 2 |
|---|---|---|---|---|---|
| 6BZ_1056 | SINKLVYLGKLFVTLNQ | U11 | 5 | 26 (4/4) | 4600 (225) |
| 6BZ_1073 | DVDELKTLYNTFILWLM | U11 | 5 | 32 (3/3) | 810 (174) |
| 6BZ_1025 | LKETILDLAALISNMNL | U14 | 8 | 32 (3/3) | 2387 (161) |
| 6BZ_107s | LFLAVFLMNSVLMIYSD | U39 | 11 | 67 (3/3) | 4210 (870) |
| 6BZ_1057 | TRTHYLLLAKNGSVFEM | U48 | 17 | 33 (4/3) | 74 (13) |
| 6BZ_1086s | ELRYFKSGLGISPPSSS | U54 | 21 | 19 (3/3) | 3858 (482) |
| 6BZ_1193 | IVLNIFALPYANVTVSN | U54 | 23 | 19 (4/3) | 5006 (1537) |
| 6BZ_1038 | MGSKIQNLFSAFPIHAF | U57 | 28 | 85 (4/3) | 324 (39) |
| 6BZ_1049s | HYSNYAIGETIPLQLII | U57 | 28 | 21 (4/3) | 11 (1) |
| 6BZ_1058 | LQLTFFFPLGIYIPTET | U57 | 28 | 17 (4/3) | 36521 (2817) |
| 6BZ_1063 | MQTLLRKSPPQFIVLTM | U57 | 28 | 20 (4/3) | 7876 (480) |
| 6BZ_1072 | NLVSLIRLVKRTISISN | U57 | 29 | 26 (3/3) | 2276 (95) |
| 6BZ_1084 | PIGSIQKLTNILSQYIS | U57 | 29 | 21 (5/ 4) | 137(5) |
| 6BZ_113 | KLFIYIITQAWTASEDS | U31 | 30 | 20 (4/3) | 37(1) |
1. Average IFN-γ response measured in fresh PBMCs; mean value (SFU/106 cells) with the number of donors testing positive over the number of donors tested shown in parenthesis
2. DRB1*01:01 binding reported as IC50 in nM, with standard deviation shown in parenthesis