Table 8. Coefficients and direction of effects from the path analyses.

	Variable 1	Direction	Variable 2	Patients		Controls
Coefficients from path analyses				Estimate	P	Estimate	P
Regression	IL-10	<—-	ABO (A, B, AB)	-0.23	2.2 × 10−11	0.068	4.5 × 10−1
Regression	VWF	<—-	ABO (A, B, AB)	0.75	8.0 × 10−111	0.85	4.2 × 10−23
Regression	Deatha	<—-	IL-10	0.038	4.9 × 10−7	NA	NA
Regression	Age	<—-	ABO (A, B, AB)	-1.01	4.6 × 10−3	0.55	4.5 × 10−1
Regression	Age	<—-	Sex (Males)	-3.81	2.6 × 10−22	-3.46 b	6.5 × 10−6
Regression	IL-10	<—-	Age	0.012	1.7 × 10−11	0.031	3.9 × 10−7
Regression	VWF	<—-	Age	0.025	3.4 × 10−48	0.024	2.5 × 10−5
Regression	IL-10	<—-	Sex	0.19	7.5 × 10−7	0.253	8.7 × 10−3
Regression	Death a	<—-	Age	0.013	4.1 × 10−75	NA	NA
Regression	Death a	<—-	Sex (Males)	0.037	2.1 × 10−2	NA	NA
Correlation	IL-10	<—>	VWF	0.14	6.7 × 10−19	0.11	4.9 × 10−3

The table shows the main results from the path analyses with regression or correlation coefficients (estimates) for ACS patient and controls separately and respective P-value. Only variables with a P-value < 0.05 are included.

^a Death is the all-cause mortality after 9 years.

^b Controls were pair wisely matched (regarding sex and age) with a subset of the ACS patients.