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. 1997 Jan 1;17(1):152–159. doi: 10.1523/JNEUROSCI.17-01-00152.1997

Fig. 2.

Fig. 2.

Clustering of Shaker-type K+ channels by DLG in heterologous cells. A, COS7 cell singly transfected with Kv1.4 and stained with anti-Kv1.4 antibodies.B, COS7 cell singly transfected with DLG and stained with anti-DLG antibodies. C, COS7 cell singly transfected with Shaker and stained with anti-Shaker antibodies. D, E, COS7 cells cotransfected with Kv1.4 and DLG and stained with anti-Kv1.4 (D) or with anti-DLG (E) antibodies. F, COS7 cells cotransfected with Shaker and dlg and stained with anti-Shaker antibodies. When expressed alone, Kv1.4, DLG, and Shaker are distributed diffusely in the cell with some perinuclear accumulation. On coexpression of DLG and Kv1.4, or DLG and Shaker, both proteins are redistributed into plaque-like clusters (D–F) that are essentially identical to those seen with PSD-95 and Kv1.4 (Kim et al., 1995). Scale bar, 10 μm.