Table 1.
Clinical Characteristics of those patients with and without a Pre-operative eGFR≤60 ml/min/1.73m2
| Characteristic | eGFR ≤60 ml/min/1.73m2 (n= 424) | eGFR >60 ml/min/1.73m2 (n=795) | P-value† |
|---|---|---|---|
| Age at time of surgery, y | 74.86 (8.49) | 69.66(10.43) | <0.001 |
| Male sex | 252 (59%) | 574 (72%) | <0.001 |
| White race | 394 (93%) | 747 (94%) | 0.5 |
| Diabetes | 174(41%) | 337 (42%) | 0.6 |
| Hypertension | 350 (83%) | 611 (77%) | 0.02 |
| Congestive Heart Failure | 133(31%) | 181 (23%) | 0.001 |
| Elective Surgery | 104(25%) | 151 (19%) | 0.02 |
| Surgery | |||
| CABG | 161 (38%) | 424 (53%) | <0.001 |
| CABG and Valve | 117 (28%) | 162(20%) | <0.001 |
| Valve | 146(34%) | 209 (26%) | <0.001 |
| Myocardial Infarction | 114(28%) | 199(26%) | 0.5 |
| Cardiac catheterization in past 48 h | 27 (6%) | 46 (6%) | 0.7 |
| Preop Serum Creatinine (mg/dL) | 1.41 (0.36) | 0.92(0.17) | <0.001 |
| Preop eGFR (ml/min/1.73m2) | 46.26(10.04) | 78.44(12.77) | <0.001 |
| Perfusion Time* | 118.29(55.89) | 112.02(61.86) | 0.02 |
| Cross Clamp time (min) | 81.84(42.08) | 75.77 (45.55) | 0.001 |
| Cardioplegia | 384(91%) | 693 (87%) | 0.08 |
| IABP | 25 (6%) | 32 (4%) | 0.1 |
| Severe AKI | 25 (6%) | 35 (4%) | 0.3 |
| Any AKI | 180(42%) | 246(31%) | <0.001 |
Note: Values tor categorical variables are given as number (percentage); tor continuous variables, as mean ± standard deviation. Conversion factor for serum creatinine in mg/dL to μmol/L, ×88.4.
*
Perfustion Time is reported for the patients who had cardiopulmonary bypass
†
Pvalues are for the comparison of patients with and without decreased pre-op GFR AKI, acute kidney injury; CABG = Coronary Artery Bypass Grafting; eGFR= estimated Glomerular Filtration Rate IABP = Intra-Aortic Balloon Pump; preop, preoperative