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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Infect Control Hosp Epidemiol. 2015 Aug 27;36(12):1379–1384. doi: 10.1017/ice.2015.201

Appendix.

Calculating the Cumulative Attributable Difference (CAD) Metric With 3 Different SIR Goals Among 3 Hypothetical Hospitals Participating in NHSN Catheter-Associated Urinary Tract Infections (CAUTI) Surveillance

CAD Equation Hospital A Hospital B Hospital C
CAD = Observed–(Predicted*SIRgoal) Observed no. = 6 (4 in
 ICUs, 2 in non-ICUs)
 Predicted no. = 2 (1 in
 ICUs, 1 in non-ICUs)
 SIR = 6/2 = 3.0
Observed no. = 20 (12 in
 ICUs, 8 in non-ICUs)
 Predicted no. = 10 (6 in
 ICUs, 4 in non-ICUs)
 SIR = 20/10 = 2.0
Observed no. = 8 (2 in
 ICUs, 6 in non-ICUs)
 Predicted no. = 10 (5 in
 ICUs, 5 in non-ICUs)
 SIR = 8/10 = 0.8
I. CAD
Number of CAUTIs that must be prevented given
 SIRgoal = 1.0 (the national baseline)
CAD = Observed–(Predicted*SIRgoal ) CAD = 6−(2 × 1.0) = 4 CAD = 20−(10 × 1.0) = 10 CAD = 8–(10 × 1.0) = −2
Number of CAUTIs that must be prevented given
 SIRgoal = 1.057 (the 2013 national SIR)
CAD = Observed–(Predicted*SIRgoal) CAD =
 6−(2 × 1.057) = 3.88
CAD =
 20–(10 × 1.057) = 9.4
CAD =
 8–(10 × 1.057) = − 2.6
Number of CAUTIs that must be prevented given
 SIRgoal = 0.75 (the HHS target)
CAD = Observed–(Predicted*SIRgoal) CAD = 6–(2 × 0.75) = 4.5 CAD =
 20–(10 × 0.75) = 12.5
CAD = 8−(10 × 0.75) = 0.5
II. CAD, stratified by location type (ICU vs non-
ICU)
Number of CAUTIs that must be prevented
 given SIRgoal = 1.18 (the 2013 national SIR in ICUs)
 and 0.8 (the 2013 national SIR in non-ICUs)
CAD = [Observed – (Predicted*SIRgoal)]ICU +
 [Observed – (Predicted*SIRgoal)]non-ICU
ICU
 CAD ICU =
 4−(1 × 1.2) = 2.8
ICU
 CAD ICU =
 12–(6 × 1.2) = 4.8
ICU
 CAD ICU =
 2–(5 × 1.2) = −4
Non-ICU
 CAD non-ICU =
 2–(1 × 0.8) = 1.2
 CAD = 2.8 + 1.2 = 4.0
Non-ICU
 CAD non-ICU =
 8–(4×0.8) = 4.8
 CAD = 4.8 + 4.8 = 9.6
Non-ICU
 CAD non-ICU =
 6–(5 × 0.8) = 2
 CAD = − 4+2 = −2

NOTE. Although the Targeted Assessment for Prevention strategy may be implemented to achieve a chosen standardized infection ratio (SIR) goal, the ultimate goal should be aimed toward elimination of healthcare-associated infections. ICU, intensive care units; NHSN, National Healthcare Safety Network; non-ICU, non–intensive care units.