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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Clin Immunol. 2015 Sep 25;161(2):291–299. doi: 10.1016/j.clim.2015.09.008

Figure 1. Effect of Misoprostol administration on ex vivo cytokine production in humans.

Figure 1

Whole blood was collected from study subjects before (Day 1) and after Misoprostol administration (Day 62) and treated ex vivo with and without LPS (1µg/ml) for overnight. TNF and IL-10 production was measured in cell free supernatants by ELISA. Data are presented as ratios of LPS-stimulated over unstimulated levels for each study subject (P1–P8). (A) TNF ratios were significantly decreased (P=0.02) and (B) IL-10 ratios were significantly increased (P=0.027) after Misoprostol administration.