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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Clin Immunol. 2015 Sep 25;161(2):291–299. doi: 10.1016/j.clim.2015.09.008

Figure 6. Misoprostol significantly increase LPS-inducible IL-10 expression in a PKA dependent manner.

Figure 6

(A) RAW cells pretreated with 10 µM Misoprostol were further stimulated with LPS, 100ng/ml, for 2 hours and IL-10 mRNA expression was analyzed by real time PCR. *P<0.05 compared to UT, aP<0.05 compared to LPS. (B) IL-10 production was measured in cell free supernatants of RAW cells treated with H89, Misoprostol and further stimulated with LPS for 6 hours. ***P<0.01 compared to LPS, aP<0.001 compared to LPS). Data are presented as means±SD, n=3.