Table 3.
Variable [Reference group] |
Univariate patient survival HR (95% CI) |
p-value | Multivariable patient survival HR (95% CI) |
p-value | |
---|---|---|---|---|---|
RECIPIENT FACTORS | |||||
Age | 1.03 (1.02–1.04) | <0.001 | 1.02 (1.01–1.03) | <0.001 | |
Male [female] | 1.30 (1.05–1.61) | 0.015 | 1.34 (1.07–1.67) | 0.010 | |
Non-caucasian [Caucasian] | 1.20 (0.97–1.49) | 0.093 | 1.08 (0.86–1.34) | 0.52 | |
Indication for LT: | |||||
HCC [non-HCC] | 1.67 (1.34–2.08) | <0.001 | 1.17 (0.90–1.51) | 0.23 | |
HCV [non-HCV] | 1.24 (1.00–1.53) | 0.048 | 1.13 (0.92–1.40) | 0.25 | |
HBV [non-HBV] | 0.73 (0.45–1.17) | 0.19 | |||
BMI at LT: | |||||
<19 [22 to 25] | 0.82 (0.53–1.27) | 0.36 | |||
19 to 21 [22 to 25] | 1.14 (0.92–1.41) | 0.25 | |||
Delta BMI | 0.89 (0.87–0.93) | <0.001 | 0.89 (0.86–0.92) | <0.001 | |
Diabetes | 1.36 (1.07–1.73) | 0.013 | 1.22 (0.96–1.56) | 0.11 | |
MELD at LT | 0.98 (0.97–1.00) | 0.014 | 1.00 (0.98–1.01) | 0.50 | |
Dialysis in week prior to LT | 1.01 (0.68–1.51) | 0.95 | |||
Hospitalization within 90 days of LT | 1.03 (0.77–1.37) | 0.84 | |||
Mechanical Ventilator | 0.57 (0.28–1.14) | 0.11 | |||
Rejection in 1st year post-LT | 1.12 (0.84–1.50) | 0.44 | |||
DONOR FACTORS | |||||
Age | 1.02 (1.01–1.02) | <0.001 | 1.01 (1.01–1.02) | <0.001 | |
Male [female] | 0.87 (0.72–1.07) | 0.19 | |||
Non-caucasian [Caucasian] | 1.27 (1.03–1.57) | 0.028 | 1.24 (1.00–1.54) | 0.055 | |
Height | 0.99 (0.98–1.00) | 0.061 | 0.99 (0.98–1.00) | 0.24 | |
Weight | 1.00 (0.99–1.01) | 0.90 | |||
BMI | 1.02 (0.99–1.04) | 0.17 | |||
DCD Allograft | 1.13 (0.71–1.80) | 0.60 | |||
Cold ischemia time | 1.02 (1.00–1.05) | 0.11 | |||
Partial or Split Liver Allografta | 0.41 (0.25–0.68) | <0.001 | |||
Deceased [Living Donor Allograft] | 2.64 (1.45–4.81) | 0.002 | 2.31 (1.25–4.24) | 0.007 |
Correlated with living donor, so not included in the multivariable model