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. 2015 Nov 25;9:630. doi: 10.3389/fnhum.2015.00630

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Copyright © 2015 Li, Zhuang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Patterns of neuronal discharge with corresponding spike trains and ISI histograms representative for STN neurons in patients with PD and LID. Five patterns were obtained from STN (n = 18 patients), including neurons with grouped discharge (A), low frequency firing (B), tonic neuronal firing (C), irregular neuronal firing (D), and tremor-related neuronal activity (E). Discharge frequencies were 37.9 ± 20.9, 24.6 ± 4.2, 71.8 ± 6.8, 49.3 ± 9.2 and 95.2 ± 15.2 Hz, respectively, for types A–E neurons.