TABLE 3.

Regression models: adjusted and unadjusted associations between manganese intake and globus pallidus T1R and T2R¹

	n	Unadjusted regression coefficients (95% CI)	Adjusted for GA regression coefficients (95% CI)
Predictor: T1R
Total manganese from birth	57	−2.6 (−4.2, −0.29)*	−3.3 (−4.4, −2.1)*
Parenteral manganese from birth	57	−14 (−21, −7.5)*	−14 (−20, −7.9)*
Total manganese 28 d before MRI	57	−3.1 (−7, −0.7)	−4.5 (−7, −2.1)*
Parenteral manganese 28 d before MRI	57	−24 (−36, −11)*	−14 (−27, −1.6)*
Whole-blood manganese	31	−2.4 (−7.9, 3)	−1.8 (−5.6, 2)
Predictor: T2R
Total manganese from birth	54	−1.1 (−1.5, −0.6)*	−1.6 (−2.9, −0.2)*
Parenteral manganese from birth	54	−3 (−6.6, 0.6)	−3 (−6.6, 0.6)
Total manganese 28 d before MRI	54	−1.7 (−2.9, −0.4)*	−1.6 (−2.9, −0.2)*
Parenteral manganese 28 d before MRI	54	2.4 (−7.1, 12)	1.5 (−8.2, 11)
Whole-blood manganese	31	0.1 (−2, 2.2)	0.1 (−2, 2.1)

¹The regression coefficients from multivariable regression models represent the unit decrease in globus pallidus T1R and T2R for each 100-unit increase in the predictor. *Statistically significant at P < 0.05. GA, gestational age; MRI, magnetic resonance imaging; T1R, T1 relaxation time; T2R, T2 relaxation time.