TABLE 3.
n | Unadjusted regression coefficients (95% CI) | Adjusted for GA regression coefficients (95% CI) | |
Predictor: T1R | |||
Total manganese from birth | 57 | −2.6 (−4.2, −0.29)* | −3.3 (−4.4, −2.1)* |
Parenteral manganese from birth | 57 | −14 (−21, −7.5)* | −14 (−20, −7.9)* |
Total manganese 28 d before MRI | 57 | −3.1 (−7, −0.7) | −4.5 (−7, −2.1)* |
Parenteral manganese 28 d before MRI | 57 | −24 (−36, −11)* | −14 (−27, −1.6)* |
Whole-blood manganese | 31 | −2.4 (−7.9, 3) | −1.8 (−5.6, 2) |
Predictor: T2R | |||
Total manganese from birth | 54 | −1.1 (−1.5, −0.6)* | −1.6 (−2.9, −0.2)* |
Parenteral manganese from birth | 54 | −3 (−6.6, 0.6) | −3 (−6.6, 0.6) |
Total manganese 28 d before MRI | 54 | −1.7 (−2.9, −0.4)* | −1.6 (−2.9, −0.2)* |
Parenteral manganese 28 d before MRI | 54 | 2.4 (−7.1, 12) | 1.5 (−8.2, 11) |
Whole-blood manganese | 31 | 0.1 (−2, 2.2) | 0.1 (−2, 2.1) |
The regression coefficients from multivariable regression models represent the unit decrease in globus pallidus T1R and T2R for each 100-unit increase in the predictor. *Statistically significant at P < 0.05. GA, gestational age; MRI, magnetic resonance imaging; T1R, T1 relaxation time; T2R, T2 relaxation time.