TABLE 4.

Regression models: adjusted and unadjusted associations between manganese intake and putamen T1R and T2R¹

	n	Unadjusted regression coefficients (95% CI)	Adjusted for GA regression coefficients (95% CI)
Predictor: T1
Total manganese from birth	57	3.3 (−4.5, −2.2)	−3.9 (−5, −2.9)*
Parenteral manganese from birth	57	−17 (−23, −11)	−17 (−22, −12)*
Total manganese 28 d before MRI	57	−6.5 (−10, −2.6)	−7.7 (−10, −5)*
Parenteral manganese 28 d before MRI	57	−26 (−37, −15)	−19 (−30, −7.1)*
Blood manganese	31	−1.6 (−7.6, 4.3)	−1.1 (−6, 3.9)
Predictor: T2
Total manganese from birth	54	−0.54 (−0.71, −0.37)	−0.59 (−0.74, −0.43)*
Parenteral manganese from birth	54	−2.5 (−3.3, −1.8)	−2.2 (−3.9, −0.54)*
Total manganese 28 d before MRI	54	−0.9 (−1.5, −0.28)	−0.98 (−1.5, −0.46)*
Parenteral manganese 28 d before MRI	54	−2.8 (−4.3, −1.3)	1.5 (−8.2, 11)
Blood manganese	31	0.22 (−0.8, 1.2)	0.28 (−0.61, 1.2)

¹The regression coefficients from multivariable regression models represent the unit decrease in putamen T1R and T2R for each 100-unit increase in the predictor. *Statistically significant at P < 0.05. GA, gestational age; T1R, T1 relaxation time; T2R, T2 relaxation time.