TABLE 4.
n | Unadjusted regression coefficients (95% CI) | Adjusted for GA regression coefficients (95% CI) | |
Predictor: T1 | |||
Total manganese from birth | 57 | 3.3 (−4.5, −2.2) | −3.9 (−5, −2.9)* |
Parenteral manganese from birth | 57 | −17 (−23, −11) | −17 (−22, −12)* |
Total manganese 28 d before MRI | 57 | −6.5 (−10, −2.6) | −7.7 (−10, −5)* |
Parenteral manganese 28 d before MRI | 57 | −26 (−37, −15) | −19 (−30, −7.1)* |
Blood manganese | 31 | −1.6 (−7.6, 4.3) | −1.1 (−6, 3.9) |
Predictor: T2 | |||
Total manganese from birth | 54 | −0.54 (−0.71, −0.37) | −0.59 (−0.74, −0.43)* |
Parenteral manganese from birth | 54 | −2.5 (−3.3, −1.8) | −2.2 (−3.9, −0.54)* |
Total manganese 28 d before MRI | 54 | −0.9 (−1.5, −0.28) | −0.98 (−1.5, −0.46)* |
Parenteral manganese 28 d before MRI | 54 | −2.8 (−4.3, −1.3) | 1.5 (−8.2, 11) |
Blood manganese | 31 | 0.22 (−0.8, 1.2) | 0.28 (−0.61, 1.2) |
The regression coefficients from multivariable regression models represent the unit decrease in putamen T1R and T2R for each 100-unit increase in the predictor. *Statistically significant at P < 0.05. GA, gestational age; T1R, T1 relaxation time; T2R, T2 relaxation time.