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Areas under the curve (AUC) and tumor/organs ratios (T/O) calculated for the main organs (% ID/g) after biodistribution (3, 24, and 48 h) of functionalized liposomes administered i.v. 24 h after BsmAb injection in LS174T-xenografted nude mice.
|
111In |
125I |
||||
|---|---|---|---|---|---|
| AUC | T/O | AUC | T/O | ||
| Tumor | 278 | 1.0 | 158 | 1.0 | |
| Blood | 437 | 0.6 | 329 | 0.5 | |
| Liver | 692 | 0.4 | 178 | 0.9 | |
| Kidneys | 371 | 0.7 | 103 | 1.6 | |
| Spleen | 1379 | 0.2 | 361 | 0.4 | |
