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. 2015 Nov 25;5:16768. doi: 10.1038/srep16768

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(A,B) Dose-dependent scratching behavior induced by intradermal (i.d.) injection of H₂S donors NaHS (20–800 μg; A) or Na₂S (20–800 μg; B). (C) No obvious scratching behavior induced by i.d. GYY4137, a slow-releasing H₂S donor. (D) No obvious scratching behavior induced by intrathecal injection of NaHS (20–100 μg). Saline injection (50 μl, i.d) serves as control. All data are expressed by means ± SEM. n = 6–8 mice per group. *P < 0.05, **P < 0.01; ***P < 0.001 vs. control, one-way AVOVA following Bonferroni post hoc test.