Skip to main content
. 2015 Nov 25;5:16719. doi: 10.1038/srep16719

Figure 2. Alum adjuvanticity is increased in GPRC6A−/− mice.

Figure 2

(a–f) 9 Wildtype (WT, gray) and 10 GPRC6A−/− (KO, white) mice were immunized with Ova/Alum by i.p. injection on day 0 and boosted on day 10. Serum samples and bone marrow samples were obtained on day 25, bone marrow supernatant was harvested on day 5 of culture, and antibody titers were measured by ELISA. (a–c,e,f) Statistical analysis was performed using t-test. Bars represent mean  ±  SEM. (d) Statistical analysis was performed using Mann-Whitney rank sum test. Boxes and whiskers represent 25–75 and 5–95 percentiles. For significant differences, levels of significance are given.