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Kinetic parameters for BPA glucuronidation in liver microsomes from WT and ΔUgt2 mice
Values are expressed as the mean ± S.D. (n = 4). Vmax is significantly different at the P < 0.0001 level and Km is not significantly different in unpaired Student’s t tests.
|
Vmax |
Km |
|
|---|---|---|
| pmol/min/mg | µM | |
| WT | 1220.0 ± 61.4 | 9.17 ± 1.73 |
| ΔUgt2 | 553.2 ± 35.2 | 7.16 ± 1.87 |
