. 2015 Dec;43(12):1872–1881. doi: 10.1124/dmd.115.066175

TABLE 3.

IC₅₀ of R- and S-atenolol inhibition of ASP+ uptake by hOCT1, hOCT2, hMATE1, and hMATE2-K

Transporter	R-Atenolol IC₅₀	S-Atenolol IC₅₀	Ratio^a	P value
	μM	μM
hOCT1	254.1 ± 11.9	206.1 ± 11.4	1.2	< 0.05
hOCT2	470.0 ± 15.2	384.0 ± 20.6	1.2	< 0.05
hMATE1	486.9 ± 22.1	645.2 ± 41.4	0.8	< 0.05
hMATE2-K	1258 ± 101.9	1194 ± 117.6	1.1	0.52

^{^a}

Ratio = R-atenolol IC₅₀/S-atenolol IC₅₀.