Table 2. Relative rates of non-synonymous (dN) and synonymous (dS) substitutions (with standard errors) calculated for bovine and Mobe DRB exon 2, averaged over all sites, the peptide binding region (PBR) and non-PBR.
| Gene |
Mobe DRB
exon2 |
BoLA DRB3
exon2 |
||||
|---|---|---|---|---|---|---|
| Overall | PBR | nonPBR | Overall | PBR | nonPBR | |
| dS (SE) | 0.10 (0.02) | 0.14 (0.03) | 0.08 (0.01) | 0.06 (0.002) | 0.14 (0.002) | 0.03 (0.002) |
| dN (SE) | 0.08 (0.01) | 0.27 (0.02) | 0.03 (0.003) | 0.09 (0.003) | 0.26 (0.01) | 0.04 (0.001) |
| dN/dS | 0.80 | 1.93 | 0.38 | 1.50 | 1.86 | 1.33 |
| Sig. test | t = 1.052, p > 0.05 | t = −7.65, P < 0.01 | t = 5.59, p < 0.01 | t = −13.83, p < 0.01 | t = −12.96, P < 0.01 | t = −4.09, P < 0.01 |
Statistical significance was tested using pair-wise T-tests.