TABLE 1.

Log K_D values obtained from ³H-CGP12177 whole cell binding in CHO-tβ1 and CHO-hβ2 cells

Values represent mean ± S.E.M. of n separate experiments.

Ligand	β1AR		β2AR
	Log KD	n	Log KD	n
Cyanopindolol	−10.46 ± 0.04	6	−10.49 ± 0.01	12
7-Methylcyanopindolol	−10.37 ± 0.03	6	−10.42 ± 0.04	14
Carazolol	−10.23 ± 0.04	5	−10.54 ± 0.04	10
(±)-Isoprenaline	−7.34 ± 0.11	5	−6.57 ± 0.08	8
ICI118551	−7.17 ± 0.06	5	−9.36 ± 0.07	10
CGP20712A	−7.76 ± 0.05	5	−5.76 ± 0.02	10

CGP20712A, 2-hydroxy-5-(2-[(hydroxy-3-[4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy]propyl)amino]ethoxy)benzamide; CHO-tβ1, CHO cells stably expressing the turkey β₁AR.