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Role of NOX in apoptotic response to TYMS inhibitors. HCT116 cells were exposed for 48 hours to TYMS inhibitors (10 µM FUra, 100 µM FdUrd, or 1 µM RTX), either alone or in the presence of 10 µM DPI, 1 µM APO, or 10 µM VAS. Apoptotic indices were measured by TUNEL assays.
