Table II.

Statistical analysis of indicators of efficacy

	Comparison	p		Comparison	p
HbS (%)	Crisis vs. HU	p<0.001	Bilirubin (mmol L−1)	Crisis vs. HbAA	p<0.01
	Crisis vs. TXN	p<0.001		Steady state vs. HbAA	p<0.001
	Crisis vs. HbSC	p<0.001		TXN vs. HbAA	p<0.01
	Steady state vs. HU	p<0.01	LDH (IU L−1)	Crisis vs. HU	p<0.001
	Steady state vs. TXN	p<0.001		Crisis vs. TXN	p<0.05
	Steady state vs. HbSc	p<0.001		Crisis vs. HbSc	p<0.001
	HU vs. TXN	p<0.001		Crisis vs. HbAA	p<0.001
	HU vs. HbSC	p<0.001	WCC (×109 L−1)	Crisis vs. HbAA	p<0.001
	TXN vs. HbSC	p<0.001		Crisis vs. HU	p<0.001
Hb (g dl−1)	Crisis vs. HbAA	p<0.001		Steady state vs. HU	p<0.001
	Crisis vs. HU	p<0.001		HbAA vs. steady state	p<0.001
	Crisis vs. steady state	p<0.01	Neutrophil (×109 L−1)	Crisis vs. steady state	p<0.05
	Crisis vs. TXN	p<0.001		Crisis vs. HU	p<0.001
	Crisis vs. HbSC	p<0.001		Crisis vs. HbAA	p<0.001
	Steady state vs. TXN	p<0.001	Reticulocytes (ml−1)	Crisis vs. HU	p<0.05
	Steady state vs. HbSC	p<0.001		Crisis vs. HbAA	p<0.001
	Steady state vs. HbAA	p<0.001		Steady state vs. HU	p<0.001
	HU vs. steady state	p<0.001		Steady state vs. HbAA	p<0.001
	TXN vs. normal	p<0.05		TXN vs. HbAA	p<0.001
HbF (%)	Crisis vs. HU	p<0.01
	HU vs. steady state	p<0.05
	HU vs. TXN	p<0.001