Table 1.

Association between the clinicopathological characteristics and Jagged1 expression (n=302)

Characteristics	Jagged1 expression in tumor tissue			Jagged1 expression in nontumor tissue			Jagged1 expression in tumor/nontumor tissue
	High	Low	P value*	High	Low	P value	High/High	High/Low	Low/High	Low/Low	P value
Age (years)			0.385			0.086					0.218
Mean ± SD †	58.3±11.3	59.8±11.6		57.3±11.1	60.1±11.6		54.6±11.2	60.2±11.0	58.5±10.9	60.1±11.7
Gender			0.377			0.736					0.751
Male	36	173		44	165		12	24	32	141
Female	20	73		18	75		7	13	11	62
Tumor size (cm)			0.169			0.407					0.120
Mean ± SD	3.41±2.46	3.83±1.98		3.56±2.16	3.80±2.05		3.91±3.28	3.14±1.91	3.40±1.45	3.92±2.06
Lauren’s classification			0.568			0.048					0.162
Intestinal	39	154		32	161		10	29	22	132
Diffuse	10	59		21	48		6	4	15	44
Mixed	7	33		9	31		3	4	6	27
Histology‡			0.103			0.982					0.124
Differentiated	18	58		16	60		4	14	12	46
Undifferentiated	38	188		46	180		15	23	31	157
Tumor depth			0.003			0.004					0.002
T1+2	27	69		29	67		10	17	19	50
T3+4	29	177		33	173		9	20	24	153
Lymph nodes metastasis			0.016			0.004					0.002
Absent	28	81		32	77		12	16	20	61
Present	28	165		30	163		7	21	23	142
Distant metastasis			0.597			0.352					0.673
Absent	56	240		62	234		19	37	43	197
Present	0	6		0	6		0	0	0	6
pTNM stage			0.008			0.011					0.009
I	22	47		22	47		9	13	13	34
II	14	59		18	55		4	10	14	45
III	20	134		22	132		6	14	16	118
IV	0	6		0	6		0	0	0	6

^*χ² test, Fisher’s exact test or one-way ANOVA was performed. P<0.05 was regarded as statistically significant.

^† SD: standard deviation.

^‡Differentiated: tub1, tub2, pap; Undifferentiated: por1, por2, sig, muc.