Figure 1.

Emodin’s anti-angiogenesis effect in human OS graft tumor in vivo. Upper part of this figure demonstrated the immunoblots of VEGF in human OS graft tumors (SOSP-9607, MG-63 and SAOS-2) harvested from nude mice. Lower part of this figure showed captured images of immunofluorescent staining of vWF in graft tumors. Ctrl: tumor bearing nude mice, Ctrl+Emodin: tumor bearing nude mice treated with emodin; Ctrl+HMGB: tumor bearing nude mice treated with HMGB; tumor bearing nude mice received co-administration of emodin and HMGB. ^aDifferences were significant when compared with Ctrl; ^cdifferences were significantly from Ctrl+Emodin.