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. 2015 Sep 15;8(9):15087–15097.

Figure 5.

Figure 5

Promotion of ERK and JNK in the MG-63 cells post the TLR-4 knockout under normoxia or hypoxia. (A) Western blot analysis of ERK or phosphorylated ERK, of JNK or phosphorylated JNK in the siRNA-TLR-4- or SIRNA-Con-transfected (60 NM) MG-63 cells under hypoxia for 24 or 48 hours; (B and C) Relative level of phosphorylated ERK to total ERK (B) or relative phosphorylated JNK or total JNK (C) in the SIRNA-TLR-4- or SIRNA-Con-transfected MG-63 cells under hypoxia. Each result was averaged for three independent experiments, and was presented as Mean ± SE. *P < 0.05, **P < 0.01.