Table 3.
Evaluation of stool consistency after TNBS induction and ZD treatment in UC rats
Stool Consistency | Day 2 | Day 5 | Day 8 |
---|---|---|---|
Normal | 0 ± 0 | 0 ± 0 | 0 ± 0 |
Model | 1.15 ± 0.45* | 2.25 ± 0.25** | 2.85 ± 0.36** |
SASP | 1.15 ± 0.5** | 2.10 ± 0.35* | 1.15 ± 0.15** |
Low dose | 1.15 ± 0.42* | 2.20 ± 0.35* | 2.55 ± 0.35* |
Moderate dose | 1.10 ± 0.35* | 2.05 ± 0.25* | 2.15 ± 0.25* |
High dose | 1.05 ± 0.25** | 1.90 ± 0.15* | 1.10 ± 0.25** |
Scoring of stool consistency: 0= no diarrhea; 1= mild; 2= severe; 3= severe and bloody diarrhea. The scores of each group were the average of 6 animals.
P<0.05 compared to model group.
P<0.01 compared to model group.
ZD, Zhenrenyangzang decoction; SASP, salazosulfapyridine.