Table 2.

Total histopathological scores of intestinal tissue

	Villus damage	Crypt damage	Cellular infiltration	Goblet cell depletion
Control (I)	0	0	0.25±0.46	0
MTX (II)	2.38±0.52	2.13±0.64	2.50±0.53	2.63±0.52
CVR (III)	1.5±0.53	1.38±0.52	1.5±0.53	1.75±0.71
PMG (IV)	2.0±0.53	1.63±0.74	2.13±0.64	2.13±0.64
p value
I-II	< 0.001	< 0.001	< 0.001	< 0.001
I-III	< 0.001	< 0.001	< 0.001	< 0.001
I-IV	< 0.001	< 0.001	< 0.001	< 0.001
II-III	0.02	0.05	0.01	0.02
II-IV	0.03	0.02	0.03	0.01
III-IV	0.161	0.574	0.105	0.328

CVR; carvacrol, PMG; pomegranate, MTX; methotrexate.