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Primary pharmacokinetic parameters after oral or intravenous administration of Indocyanine Green in rats (n = 6)
| Parameters | Unit | Mean | SD |
|---|---|---|---|
|
| |||
| Intravenous, 15 mg/kg | |||
| AUC(0-t) | ng/mL *min | 501111.2 | 256317.6 |
| AUC(0-∞) | ng/mL *min | 503070.1 | 255807.0 |
| t1/2 | min | 79.5 | 29.2 |
| MRT(0-t) | min | 5.8 | 4.7 |
| MRT(0-∞) | min | 9.1 | 9.5 |
| CL | L/min/kg | 0.02 | 0.03 |
| V | L/kg | 2.7 | 4.1 |
| Cmax | ng/mL | 68095.1 | 37439.8 |
